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Title(s)
Title | Language |
Codon Wizard programe | en |
Author(s)
Name | ORCID | GND | Affiliation |
Rehbein, Peter | |||
Berz, Jannik | |||
Kreisel, Patrick |
Contributor(s)
Name | ORCID | GND | Affiliation | Role |
ContactPerson |
Faculty
14 Biochemistry, Chemistry and Pharmacy
DFG-Subject
201-01 Biochemistry
Date Issued
04 April 2019
Publisher(s)
Institute for Applied Biotechnology, University of Applied Sciences Biberach
Goethe-Universität Frankfurt
Type(s) of data
Software
Language(s)
en
Subject Keyword(s)
Abstract(s)
Abstract | Language |
Optimization of coding sequences to maximize protein expression yield is often outsourced to external service providers during commercial gene synthesis and thus unfortunately remains a black box for many researchers. The presented software program "CodonWizard" offers scientists a powerful but easy-to-use tool for customizable codon optimization: The intuitive graphical user interface empowers even scientists inexperienced in the art to straightforward design, modify, test and save complex codon optimization strategies and to publicly share successful optimization strategies among the scientific community. "Codon Wizard" provides highly flexible features for sequence analysis and completely customizable modification/optimization of codon usage of any given input sequence data (DNA/RNA/peptide) using freely combinable algorithms, allowing for implementation of contemporary, well-established optimization strategies as well as novel, proprietary ones alike. Contrary to comparable tools, "Codon Wizard" thus finally opens up ways for an empirical approach to codon optimization and may also >be used completely offline to protect resulting intellectual property. | en |
Related Resource(s)
Type of identifier | Identifier | Type of publication | Type of relation |
DOI | 10.1016/j.pep.2019.03.018 | JournalArticle | IsSupplementTo |
License
All rights reserved
Views
12
Acquisition Date
Mar 14, 2025
Mar 14, 2025
Downloads
1
Acquisition Date
Mar 14, 2025
Mar 14, 2025