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  4. F14 - Faculty of Biochemistry, Chemistry and Pharmacy
  5. Faculty of Biochemistry, Chemistry and Pharmacy: Research Data
  6. Codon Wizard programe
 
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Title(s)
TitleLanguage
Codon Wizard programe
en
 
Author(s)
NameORCIDGNDAffiliation
Schwalbe, Harald Jochen 
0000-0001-5693-7909
Organic Chemistry and Chemical Biology 
Rehbein, Peter
University of Applied Sciences Biberach 
Berz, Jannik
Molecular Bio Sciences 
Kreisel, Patrick
Molecular Bio Sciences 
 
Contributor(s)
NameORCIDGNDAffiliationRole
Ferner, Jan-Peter 
0000-0002-2009-3203
Organic Chemistry and Chemical Biology 
ContactPerson
 
Faculty
14 Biochemistry, Chemistry and Pharmacy
 
DFG-Subject
201-01 Biochemistry
 
Date Issued
04 April 2019
 
Publisher(s)
Institute for Applied Biotechnology, University of Applied Sciences Biberach
Goethe-Universität Frankfurt
 
Handle
https://gude.uni-frankfurt.de/handle/gude/517
 
DOI
10.25716/gude.09m5-0yj9
 

Type(s) of data
Software
 
Language(s)
en
 
Subject Keyword(s)
  • Protein

  • Expression

  • Sequence

  • Codon

  • Optimization

  • Software

 
Abstract(s)
AbstractLanguage
Optimization of coding sequences to maximize protein expression yield is often outsourced to external service providers during commercial gene synthesis and thus unfortunately remains a black box for many researchers. The presented software program "CodonWizard" offers scientists a powerful but easy-to-use tool for customizable codon optimization: The intuitive graphical user interface empowers even scientists inexperienced in the art to straightforward design, modify, test and save complex codon optimization strategies and to publicly share successful optimization strategies among the scientific community. "Codon Wizard" provides highly flexible features for sequence analysis and completely customizable modification/optimization of codon usage of any given input sequence data (DNA/RNA/peptide) using freely combinable algorithms, allowing for implementation of contemporary, well-established optimization strategies as well as novel, proprietary ones alike. Contrary to comparable tools, "Codon Wizard" thus finally opens up ways for an empirical approach to codon optimization and may also >be used completely offline to protect resulting intellectual property.
en
 

Related Resource(s)
Type of identifierIdentifierType of publicationType of relation
DOI
10.1016/j.pep.2019.03.018
JournalArticle
IsSupplementTo
 

License
All rights reserved
 

Views
18
Acquisition Date
May 9, 2025
View Details
Downloads
2
Acquisition Date
May 9, 2025
View Details

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